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| ASCCA Research ASCCA Clinician Scientist Award
Dr. Pratik Pandharipande is an Assistant Professor in the Department of Anesthesiology, Division of Critical Care at Vanderbilt University School of Medicine. He is Board Certified in Anesthesiology with a Subspecialty Certification in Critical Care Medicine. Dr Pandharipande graduated with a MB, BS (MD) from University of Nagpur in India. He then completed an Anesthesiology Residency at Saint Barnabas Medical Center, N.J. followed by a Fellowship in Critical Care – Anesthesia at Vanderbilt University Medical Center. Dr Pandharipandes' research interests are in the pathogenesis of delirium or acute brain dysfunction in critically ill patients, and the role of sedatives and analgesic medications in delirium. Based on some of his previous work, he hypothesizes that the standard use of GABA agonist sedatives such as lorazepam and propofol may contribute to ICU delirium and its attendant untoward clinical outcomes. An alternative sedation strategy targeting alpha2 receptors and sparing GABA receptors might reduce delirium, provide adequate sedation, reduce analgesic requirement, and concurrently improve cognitive performance. Dr Pandharipande is presently conducting a blinded, randomized controlled trial of adult mechanically ventilated patients using a sedation strategy of dexmedetomidine ± fentanyl versus lorazepam ± fentanyl, with relevant outcomes and safety monitoring. The specific aims of his study are to:
This grant is made possible through the support of Abbott Laboratories and is known as the ASCCA - FAER - Hispira Physician Scientist Award. Interested candidates should submit their applications to FAER, following the FAER Research Training Grant (RTG) guidelines and format. Candidates need only indicate specific interest in the ASCCA award. The physician scientist award provides research funding in the amount of $75,000 per year for two years. The research grant award requires 80 percent time and mentorship by a senior mentor with a history of training individuals, who develop independent research programs. The mentor should have a strong portfolio of active extramural (usually NIH) funding. The applicant must be board-eligible, or certified in both anesthesiology and critical care, and provide convincing evidence of a long-range commitment to an investigative career. A wide spectrum of research will be deemed appropriate for funding for the physician scientist award given the tremendous diversity of pathophysiology that relates to critical care medicine. Interested individuals are encouraged to apply for the award.
Previous Year’s Award Recipients
Guido Musch, M.D. of the Massachusetts General Hospital. Title
of Research Project - "Regional Effects of Alveolar Recruiting
Strategies on Gas Exchange and Cellular Inflammation in Acute Lung
Injury."
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The
American Society of Critical Care Anesthesiologists and the Foundation
for Anesthesia Education and Research are pleased to announce the
recipient of a joint two-year research training grant (RTG) for
new physician scientists working with a well-established mentor
doing either basic science or clinical research. This year’s
recipient is Pratik Pandharipande, M.B., B.S. of the Vanderbilt
University School of Medicine. He is studying "A Randomized,
Double-Blind Trial in Ventilated ICU Patients Comparing Treatment
with an Alpha 2 Agonist Versus a Gamma Aminobutyric Acid (GABA)
– Agonist to Determine Delirium Rates, Efficacy of Sedation
and Analgesia, and Clinical Outcomes Including Duration of Mechanical
Ventilation and 3 Month Cognitive Status." His grant will run
for two years, July 2005, through June 2007.
January
2004 – December 2005